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Ichilov Medical Center
Oncology

Treatment of CD30-Positive B-Cell Lymphoma in Israel

Ihilov, one of the leading Israeli clinics, is globally renowned for its advanced technologies and high treatment efficacy. This multidisciplinary medical institution attracts patients from all over the world who hope to overcome the most complex diseases. Israeli doctors have achieved outstanding results in the treatment of CD30-positive B-cell lymphoma, demonstrating high professionalism and international qualifications. Modern treatment methods, a collegial approach, and an individualized approach to each patient make Ihilov one of the best choices for those seeking effective treatment for this disease.

>80%
of patients choose an online consultation with an Israeli expert even before arriving at the clinic
>30%
of patients received innovative treatments unavailable in their home clinics
1726
patients underwent comprehensive examination and treatment under the guidance of Israeli doctors while staying at home

Treatment of CD30-Positive B-Cell Lymphoma in Israel

Patients at Ihilov clinic are provided with comfortable accommodation and a high level of service. Foreigners have access to a personal assistant service, which helps with all organizational issues and ensures a comfortable stay in Israel. This allows patients to fully focus on their health and recovery.

About the Disease

CD30-positive B-cell lymphoma is a malignant disease characterized by uncontrolled growth of a specific type of white blood cells – B-lymphocytes, which have a specific marker CD30 on their surface. These cells begin to proliferate abnormally quickly, forming tumours in lymph nodes, spleen, bone marrow, and other organs.

The development of the disease is influenced by genetic mutations, exposure to viruses and other infectious agents, as well as immune disorders. As a result of these factors, the normal maturation and functioning process of B-lymphocytes is disrupted, and the cells begin to transform into tumour cells.

Patients may experience various symptoms depending on the location and size of the tumours. Common symptoms include swollen lymph nodes, elevated body temperature, night sweats, unexplained weight loss, fatigue, and skin itching. Additionally, tumours can compress surrounding organs and tissues, causing pain, shortness of breath, difficulty swallowing, and other symptoms.

Treatment Methods for CD30-Positive B-Cell Lymphoma

The choice of treatment method or their combination is determined by the attending physician based on a thorough examination of the patient and assessment of all risk factors. In most cases, treatment of CD30-positive B-cell lymphoma is conducted using combined methods, which allow for achieving higher results and reducing the risk of tumour cell resistance. Combinations of chemotherapy, targeted therapy, immunotherapy, and radiation therapy are tailored individually for each patient depending on the stage of the disease and other factors.

Chemotherapy

Chemotherapy is one of the main treatment methods for CD30-positive B-cell lymphoma and is used in both early and late stages of the disease. This method is based on the use of cytostatic drugs that suppress the growth of tumour cells. There are many different chemotherapy regimens, the choice of which depends on the stage of the disease, the overall condition of the patient, and other factors. Modern chemotherapeutic agents have high efficacy and lower toxicity compared to those of previous generations.

Targeted Therapy

Targeted therapy is a promising treatment method aimed at targeting specific molecules involved in the growth and development of tumour cells. In CD30-positive B-cell lymphoma, drugs that block the CD30 receptor are used, leading to the death of tumour cells. This method is characterized by high selectivity and fewer side effects compared to traditional chemotherapy. In Israel, the latest targeted drugs are widely used, allowing many patients to achieve long-lasting remission.

Immunotherapy

Immunotherapy is an innovative treatment method aimed at enhancing the body's own defense mechanisms. In CD30-positive B-cell lymphoma, monoclonal antibodies are used that bind to tumour cells and make them more vulnerable to the immune system. Additionally, drugs that stimulate the activity of immune cells are used. Immunotherapy demonstrates high efficacy in treating recurrent and resistant forms of the disease.

Radiation Therapy

Radiation therapy is used to destroy tumour cells using ionizing radiation. This method can be used as a standalone treatment or in combination with other methods. Radiation therapy allows for precise targeting of the tumour while minimizing damage to healthy tissues. Modern linear accelerators and treatment planning systems ensure high precision in radiation delivery.

Hematopoietic Stem Cell Transplantation

Hematopoietic stem cell transplantation is a highly effective treatment method used for recurrent and resistant forms of the disease. This method involves transplanting healthy stem cells that restore the patient's bone marrow and immune system. Transplantation can be autologous (using the patient's own stem cells) or allogeneic (using donor stem cells). In Israel, transplants are performed using the latest

  • Stem cell therapy
  • Radiation therapy
  • Chemotherapy

Diagnostic Methods for the Disease

Diagnosis at Ihilov is conducted at the highest level, which is crucial for establishing the correct diagnosis and selecting the most effective treatment. The accuracy of diagnosis plays a key role, as it determines the success of therapy and the prognosis for the patient.

First Day

Upon arrival at the clinic, the patient is directed to a consultation with the attending physician. The doctor collects a detailed medical history, conducts an examination, and assesses the overall condition of the patient. Based on the information obtained, the doctor prescribes a series of tests that will provide a complete picture of the disease and accurately determine the stage of the lymphoma.

Second Day

List of laboratory and instrumental studies:

  • Complete blood count
  • Biochemical blood test
  • Immunohistochemical study
  • Tumour marker analysis (including CD30)
  • PET-CT (positron emission tomography)
  • MRI (magnetic resonance imaging)
  • Lymph node biopsy
  • Bone marrow trepanobiopsy
  • Genetic testing for mutations
  • Abdominal ultrasound
  • Chest X-ray
  • ECG (electrocardiogram)

Third Day

On the third day, a team of specialists gathers to discuss the diagnostic results and develop a therapeutic plan. The process involves a hematologist, oncologist, radiologist, surgeon, and other narrow-profile specialists. A multidisciplinary approach allows for considering all aspects of the disease, developing a personalized treatment plan, and selecting optimal therapy methods, significantly increasing the chances of successful treatment.

  • Biopsy
  • Computed tomography
  • Magnetic Resonance Imaging (MRI)
  • Diagnosis – PET CT

How Much Does Treatment Cost in Israel

The cost of treatment for CD30-positive B-cell lymphoma is calculated based on numerous factors, including the type and duration of therapy, the medications used, the need for additional procedures, and the length of stay in the clinic. Each case is individual, and therefore the exact cost may vary.

To obtain a price estimate for a specific case, contact the consultant at the phone number provided on this website. The consultant will provide detailed information about the cost of treatment, including possible additional expenses and payment options.

Advantages of Treatment in Israel

  1. The most advanced treatment methods, including immunotherapy, targeted therapy, and other innovative approaches.
  2. Leading world oncologists with extensive experience in treating various types of lymphomas.
  3. An individualized treatment plan that takes into account the specifics of the disease and the patient's body.
  4. State-of-the-art medical equipment that allows for precise diagnosis and effective treatment of patients.
  5. Comfortable accommodation, meals, and all necessary services.

Do not delay visiting a doctor at the first signs of symptoms! Even before arriving in Israel, you can get an online consultation with a specialist by providing the results of preliminary studies. The doctor will give you specific recommendations and help you choose the most suitable treatment method.

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Attach your discharge notes and imaging — Ichilov physicians will review and propose an optimal plan.

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