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Ichilov Medical Center
Endocrinology

Treatment of Diabetic Nephropathy in Israel

Israeli medicine is renowned for its innovations and advanced technologies, which are practically applied at the Ichilov clinic in the treatment of diabetic nephropathy. Specialists at the center use a comprehensive approach that organically combines precise diagnostics with personalized therapeutic programs. Among modern methods, hemodialysis with high-precision real-time monitoring systems occupies a special place, significantly increasing the effectiveness of procedures. Thanks to this approach, patients achieve stable disease control, and treatment results often exceed expectations.

>80%
of patients choose an online consultation with an Israeli expert even before arriving at the clinic
>30%
of patients received innovative treatment unavailable in domestic clinics
2384
patients have used the services of integrative medicine

The comfort of accommodation at the Ichilov clinic is at a high level. The rooms resemble hotel suites and are equipped with everything necessary to facilitate rapid recovery. Care is provided by experienced specialists around the clock. Patients can take advantage of personal escort services. This service simplifies all processes and provides confidence in every step.

About the disease

Treatment of Diabetic Nephropathy in IsraelDiabetic nephropathy is a progressive damage to the renal vessels and glomeruli caused by prolonged hyperglycemia in diabetes mellitus. The disease progresses through five stages: initial hyperfunction of the kidneys is followed by microalbuminuria, then proteinuria, chronic kidney failure develops, and it culminates in the terminal stage requiring dialysis.

Causes

  • Chronic hyperglycemia
  • Arterial hypertension
  • Genetic predisposition
  • Dyslipidemia

Symptoms

  • Swelling of the face and limbs
  • Increased blood pressure
  • Proteinuria
  • Decreased appetite
  • Weakness and fatigue
  • Nausea

Treatment methods

At Ichilov, the choice of treatment methods for diabetic nephropathy is based on comprehensive diagnostics, including the assessment of glomerular filtration rate, albuminuria levels, and associated complications of diabetes.

Medication therapy

In the early stages of the disease, doctors prescribe a comprehensive medication therapy aimed at slowing the progression of kidney damage. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers protect the renal glomeruli from damage by reducing intraglomerular pressure. Concurrently, medications for glycemic control are used, including modern sodium-glucose cotransporter inhibitors, which not only normalize blood sugar levels but also have a direct nephroprotective effect. Statins correct lipid metabolism, reducing atherosclerotic damage to the renal vessels.

Dialysis therapy

In the terminal stage of kidney failure, replacement kidney therapy is applied. Hemodialysis is performed on state-of-the-art machines with high-flow membranes that effectively remove toxins and excess fluid from the blood. Procedures are carried out three times a week under the supervision of nephrologists, who individually adjust blood purification parameters. An alternative is peritoneal dialysis, where the patient's abdominal cavity is used as a natural filter. This method provides gentler and continuous cleansing, allowing the residual kidney function to be preserved longer.

Plasmapheresis

This method of extracorporeal detoxification is used in rapidly progressing forms of nephropathy with high proteinuria. The patient's blood is passed through a special blood separator, where plasma with accumulated toxins, immune complexes, and excess lipids is separated and replaced with donor plasma or albumin. A course of five to seven procedures helps to quickly improve kidney function and reduce inflammatory activity. Plasmapheresis is particularly effective when diabetic nephropathy is combined with autoimmune processes or resistant hyperlipidemia.

Correction of mineral-bone disorders

As kidney function declines, secondary hyperparathyroidism and disturbances in phosphorus-calcium metabolism develop, requiring specialized treatment. Doctors prescribe phosphate-binding agents that are taken with meals and prevent the absorption of excess phosphorus from the intestine, protecting vessels from calcification. Active forms of vitamin D are used to suppress excessive secretion of parathyroid hormone and improve calcium absorption by bone tissue. Regular laboratory monitoring allows tracking levels of calcium, phosphorus, and parathyroid hormone, adjusting therapy until target indicators are reached and preventing the development of renal osteodystrophy with pathological fractures.

Diet therapy

A individually developed diet becomes an integral part of treatment at all stages of the disease. Dietitians at Ichilov create meal plans with protein restriction to a certain level, reducing the load on damaged nephrons. Sodium intake is controlled to prevent swelling and hypertension, while potassium and phosphorus are limited as kidney function declines. Patients receive recommendations for choosing foods with a low glycemic index, which provide stable glucose levels without sharp fluctuations. Regular consultations help to adapt the diet to the changing condition of the kidneys.

Lifestyle modification

Modifying everyday habits plays a critical role in slowing the progression of nephropathy. Specialists develop programs for dosed physical activity, taking into account the functional state of the kidneys and cardiovascular system. Moderate-intensity aerobic exercises improve glycemic control and reduce blood pressure without overloading the body. Complete cessation of smoking becomes a mandatory component, as nicotine accelerates the sclerosis of renal vessels. Psychological support helps patients cope with stress and adhere to long-term recommendations.

Diagnostic methods for the disease

The diagnosis of diabetic nephropathy at the Ichilov clinic is conducted on high-precision modern equipment, ensuring maximum accuracy of results. All procedures are planned in advance and carried out in a short time, allowing the patient to quickly obtain a complete picture of the disease.

First day

Upon arrival, the patient immediately sees a leading nephrologist. The doctor collects a detailed medical history, conducts a thorough examination, and orders necessary tests to assess kidney condition and overall health.

Second day

On this day, all key diagnostic procedures are performed:

  • Complete blood count
  • Biochemical blood test (including creatinine, urea, glucose, electrolytes)
  • Urine test for microalbumin and daily proteinuria
  • Creatinine clearance (calculated glomerular filtration rate)
  • Kidney ultrasound with Doppler imaging of vessels
  • ECG

Third day

The attending physician gathers a consultation with the participation of a nephrologist, endocrinologist, cardiologist, and other specialized specialists. This approach allows for the creation of the most relevant and individualized treatment plan, taking into account all patient characteristics.

  • Electrocardiography and Doppler imaging
  • Ultrasound
  • Blood biochemistry

How much does treatment cost in Israel

The cost of treating diabetic nephropathy in Israel is determined by the volume of diagnostics, the chosen method of therapy, the duration of stay in the clinic, and the necessary rehabilitation. The price depends on the stage of the disease, individual patient characteristics, and the technologies used.

For an accurate calculation of the cost in a specific case, please contact the clinic consultant at the phone number listed on the website. The consultant will provide a personal calculation, answer all questions, and help organize treatment.

Advantages of treatment in Israel

  1. Highly qualified nephrologists and endocrinologists with international experience.
  2. Advanced diagnostic and treatment methods on the latest equipment.
  3. Individual therapy programs considering all comorbidities.
  4. Modern dialysis systems and innovative medications to slow progression.
  5. Comfortable accommodation conditions and a full range of accompanying services.

Even before arriving at the Israeli clinic, the patient can order an online consultation with the necessary specialist. As a result, they will receive personal recommendations, answers to questions, and detailed information about available modern technologies for treating diabetic nephropathy.

Get a treatment plan

Attach your discharge notes and imaging — Ichilov physicians will review and propose an optimal plan.

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