The new Corify Care technology detects arrhythmia in a single heartbeat, showing all four chambers of the heart simultaneously

The team from the Polytechnic University of Valencia, in collaboration with Corify Care, has made a significant breakthrough in the field of cardiac electrophysiology by presenting the world's first global volumetric mapping technology. The research results were published in the prestigious scientific journal Nature Communications Medicine, confirming the high level of scientific significance of the development.

For the first time in the history of cardiology, a system has been created that can simultaneously map all four chambers of the heart and provide doctors with a comprehensive view of cardiac arrhythmias in real-time over a single cardiac cycle. This is a fundamentally new approach that radically differs from all existing solutions on the market.

A revolution in arrhythmia diagnosis

Before the advent of Corify Care technology, all existing mapping systems analyzed each chamber of the heart separately, forcing doctors to make assumptions and conclusions about what they could not physically see. This created significant "blind spots" in diagnostics and severely limited the ability to accurately plan treatment for complex arrhythmias.

The new technology, developed in the laboratories of the ITACA Institute at the Polytechnic University of Valencia, completely changes this paradigm. The advanced Corify system allows visualization not only of the surface of the heart but also of its internal structure, including the walls and septum between the chambers. The technology provides a complete map of the entire heart in a single cardiac cycle, demonstrating in real-time how arrhythmias spread across the walls of the heart and between chambers before and during the ablation procedure.

"It's about transparency and confidence. We provide doctors with a complete picture from the very beginning, rather than fragments. A global overview means faster decisions, more targeted ablation, and the potential to reduce the time and complexity of the procedure," explains Andreu Climent, PhD, CEO of Corify Care and a researcher at the Polytechnic University of Valencia.

Detection of hidden arrhythmia pathways

The Corify Care system is capable of identifying pathways of arrhythmia propagation that often go unnoticed when using traditional diagnostic tools. This includes complex arrhythmic circuits located deep within the walls of the heart, as well as pathways that span multiple chambers of the heart. By eliminating these critical "blind spots," the platform helps doctors address even the most complex clinical cases more effectively and predictably.

"For the first time, we can non-invasively see the heart as it truly is: as a whole," emphasizes Dr. Felipe Atienza, chief physician and head of the cardiology department at Gregorio Marañón University Hospital in Madrid. "This has significant implications for workflow organization, improving clinical outcomes, and the scalability of electrophysiological laboratories."

Scientific justification

Jorge Vicente-Puig, PhD and lead author of the study, emphasizes that this work convincingly demonstrates the need for a volumetric approach to truly characterize arrhythmia: "We have overcome the mathematical limitations of the past and obtained a complete three-dimensional physiological image of a functioning heart. This opens up entirely new possibilities for understanding the mechanisms of arrhythmia onset and development."

The study involved leading experts from several prestigious medical and scientific institutions, including the Autonomous University of Barcelona, the Clinical Hospital of Barcelona at the University of Barcelona, the August Pi i Sunyer Biomedical Research Institute IDIBAPS, the Karlsruhe Institute of Technology in Germany, and the Biomedical Research Center for Cardiovascular Diseases (CIBERCV).

Regulatory status and development prospects

Corify Care is actively working on integrating its system with leading catheter navigation platforms to ensure a seamless hybrid workflow. At the same time, several new research directions are being developed, including expanded volumetric data analysis. The results of current research will be presented to the medical community at the upcoming Atrial Fibrillation Symposium 2026 in Boston.