Israel should definitely be on your shortlist for treatment abroad. In Israel, not only is the cost of treatment lower than in Western Europe and the USA, but you will also have access to advanced research and procedures for treating lymphoma.The effectiveness of therapy is increasing every year, even patients with late-stage disease have a chance for recovery.
A whole team of doctors is involved in the treatment of patients with mediastinal lymphoma. Among them are oncologists known not only in Israel – Arnon Negler, Amos Cohen, Gidi Rahbi, who have been repeatedly invited for consultations at leading American and European clinics.
Patients arriving for treatment at Ichilov are accommodated in cozy rooms where they will feel comfortable, assisted by the staff of the clinic's international department. Reviews of mediastinal lymphoma treatment at Ichilov can be read on this website.
Treatment Methods for Mediastinal Lymphoma
Primary large cell mediastinal lymphoma grows quickly and requires prompt treatment. The main goal is to eliminate all signs of lymphoma and achieve stable remission. The treatment approach depends on the stage of lymphoma and the presence of symptoms causing problems. The most common treatment methods are presented below.
Immunotherapy and Chemotherapy
Mediastinal lymphoma is often treated with a combination of the immunotherapeutic drug rituximab and chemotherapy. This is called chemoimmunotherapy. Commonly used combinations of chemoimmunotherapy for PMBCL include:
- R-CHOP
- DA-EPOCH-R – etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab. “DA” means “dose-adjusted”. This means that the dose of medications can be adjusted based on how your body responds to treatment.
Steroids
Steroids are medications that are often prescribed alongside chemotherapy for treating lymphomas. They help make chemotherapy more effective.
Radiation Therapy
Radiation therapy uses high-energy beams to destroy cancer cells while causing as little harm as possible to normal cells. Some patients are prescribed radiation therapy after chemotherapy and rituximab for treating mediastinal lymphoma. This method can also reduce the risk of lymphoma recurrence in this area.
Stem Cell Transplantation
Stem cell transplantation is used to treat lymphoma in case of relapse. Stem cell transplantation is an intensive treatment method, so it is not suitable for everyone. The transplantation can be done using the patient's own stem cells – autologous stem cell transplant – or cells from a donor transplant – allogeneic stem cells.
CAR-T Cell Therapy
CAR-T cell therapy is sometimes used to treat relapsed mediastinal lymphoma. CAR-T therapy (chimeric antigen receptor therapy) involves collecting the patient's own immune cells and reprogramming them. The cells are then used as treatment to target lymphoma cells. CAR-T therapy is also used when lymphoma progresses and when other treatment methods have not helped.
- Radiation therapy
- Bone marrow transplantation in Israel
- Chemotherapy
Diagnostic Methods for Mediastinal Lymphoma
A comprehensive examination at Ichilov Clinic, which allows identifying all causes of the patient's poor health and making an accurate diagnosis, usually takes place in three stages and lasts three days, not including the time needed to complete some laboratory tests.
Initial Consultation
The patient visits a specialist doctor in the diagnostics department. He conducts a medical examination, reviews the medical history, and refers the patient for laboratory and instrumental studies. If the patient has bone marrow biopsy materials, they are sent for review.
Diagnostic Tests
The next morning, the patient undergoes a blood laboratory test.
Then a PET-CT or similar imaging studies (CT, MRI) are performed. This instrumental examination helps determine the stage and extent of cancer.
The most common test for confirming the diagnosis is a biopsy. The doctor will take a tissue sample from the affected area. Most often, a biopsy is taken from an enlarged lymph node.
All procedures and consultations are organized by a medical coordinator, who also provides translation into Hebrew.
Consultation, Treatment Planning
When the examination results are ready, the attending physician gathers an expert commission consisting of doctors who will participate in the treatment process. These are experts from related fields of medicine – oncologists, thoracic surgeons, radiologists, chemotherapists, bone marrow transplantation specialists. The doctors will collegially discuss the clinical case and develop an individualized treatment plan that best meets the patient's needs. After the consultation, the attending physician will discuss the advantages of the chosen methods with the patient and inform him of the possible risks, as well as provide an overall prognosis.
- Biopsy
- Computed Tomography
- Magnetic Resonance Imaging (MRI)
- Diagnosis – PET CT
How Much Does Treatment Cost
The cost of treatment always consists of the cost of all therapeutic and diagnostic procedures, bed days, and consultations received by the patient. From case to case, depending on the patient's condition and specific indications, the cost may vary significantly. The final price is announced after a comprehensive examination at the clinic. An approximate cost can be requested at the stage of preparing for the trip. To do this, you need to fill out any of the application forms, call, or request a callback. Our consultant will contact you to discuss important details and provide a price estimate.
Advantages of Treatment in Israel
- High level of physician training: most Israeli doctors train in the best clinics in the world.
- Use of advanced high-tech diagnostic and treatment methods with an increased level of safety.
- Affordable prices, allowing patients to save on individual services by up to 30-45% compared to competing clinics in Europe.
- Personal case managers who resolve all organizational and logistical issues, ensuring maximum comfort during the stay in the clinic.
If you are interested in a consultation with a specialist from an Israeli clinic, fill out the application form on our website, call, or request a callback. Timely treatment always improves the prognosis.